The Metropolitan Opera is set to present the world-premiere staging of composer Kevin Puts’s “The Hours.”

The opera, which is set to be presented between Nov. 22 and Dec. 15, is adapted from Michael Cunningham’s acclaimed novel. The work will see the return of Renée Fleming, who has not performed with the company since 2017, in the role of Clarissa Vaughan. She will be joined by Kelli O’Hara and Joyce DiDonato as Laura Brown, and Virginia Woolf.

Met Music Director Yannick Nézet-Séguin returns to the Met podium for teh first time this season conducting the production by Phelim McDermott. The cast will also include mezzo-soprano Denyce Graves as Sally, Clarissa’s partner; soprano Kathleen Kim as Barbara and Mrs. Latch; soprano Sylvia D’Eramo as Kitty and Vanessa; countertenor John Holiday as the Man Under the Arch and the Hotel Clerk; bass-baritone Kyle Ketelsen as Richard, Clarissa’s best friend who is dying from AIDS; tenor William Burden as Louis, Richard’s ex-boyfriend; tenor Sean Panikkar as Leonard Woolf, Virginia Woolf’s husband; and bass-baritone Brandon Cedel as Dan Brown, Laura Brown’s husband.

Kensho Watanabe conducts the Dec. 15 performance of “The Hours.”

“The Hours” was inspired by Virginia Woolf’s “Mrs. Dalloway,” and was adapted into an Oscar-winning film version starring Meryl Streep, Julianne Moore, and Nicole Kidman.

On Dec. 10, the opera will be transmitted live to movie theaters around the globe as part of the Met’s Live in HD series. The Nov. 22 and Dec. 7 and 10 performances will be broadcast live on Metropolitan Opera Radio on SiriusXM Channel 355.