Targetti graduated cum laude in Architecture at the University in Milan, his native town; he simultaneously studied Piano at the Scuola Musicale di Milano and Voice with Professor Carla Castellani.
After working as an Architect for a few years, he became an artists manager from 1986 to 1997 in Milan, Naples, and Munich. He would become the Teatro alla Scala’s Casting Director working in the Artistic Department. He would then become the head of International Projects at the Academy of La Scala for three years.
In 2011, he returned to his previous profession, artists manager, contributing to the creation of InArt Managment, which manages the careers of such artists as Lisette Oropesa, Leah Crocetto, Corinne Winters, Luca Salsi, J’nai Bridges, Francesco Meli, and Brian Jagde, among others.
A number of singers have mentioned his passing on social media including Yusif Eyvazov, Martin Muehle, Elizabeth de Trejo, Laura Aikin, and Corinne Winters among others.