The Teatro San Carlo has announced two cast changes for its March 12 performance of Verdi’s “Macbeth.”

The company said that due to illness Sondra Radvanovsky will not sing the role of Lady Macbeth and will be replaced by Daniela Schillaci. Meanwhile, George Gagnidze will sing the title role taking over for Luca Salsi.

Schillaci performed the role on opening night on March 9. The soprano has sung at the Teatro La Fenice in Venice, the Teatro Massimo Bellini in Catania, the Teatro Verdi di Trieste, and Opera di Roma. Gagnidze is a recognized Verdi baritone who has sung the role of Macbeth at the Metropolitan Opera, Palau de les Arts, and Opera de las Palmas.

The two singers lead a cast that includes Alexander Vinogradov, Giulio Pelligra, and Francesco Castoro. Marco Armiliato conducts.